Nalaganje...

N-Glycosylation Is Required for Matriptase-2 Autoactivation and Ectodomain Shedding

Matriptase-2 is a hepatic membrane serine protease that regulates iron homeostasis. Defects in matriptase-2 cause iron deficiency anemia. In cells, matriptase-2 is synthesized as a zymogen. To date, how matriptase-2 expression and activation are regulated remains poorly understood. Here we expressed...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Jiang, Jiang, Yang, Jianfeng, Feng, Ping, Zuo, Bin, Dong, Ningzheng, Wu, Qingyu, He, Yang
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094060/
https://ncbi.nlm.nih.gov/pubmed/24867957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.555110
Oznake: Označite
Brez oznak, prvi označite!