Crystallographic and Glycan Microarray Analysis of Human Polyomavirus 9 VP1 Identifies N-Glycolyl Neuraminic Acid as a Receptor Candidate

Human polyomavirus 9 (HPyV9) is a closely related homologue of simian B-lymphotropic polyomavirus (LPyV). In order to define the architecture and receptor binding properties of HPyV9, we solved high-resolution crystal structures of its major capsid protein, VP1, in complex with three putative oligos...

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Bibliographic Details
Main Authors: Khan, Zaigham Mahmood, Liu, Yan, Neu, Ursula, Gilbert, Michel, Ehlers, Bernhard, Feizi, Ten, Stehle, Thilo
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093890/
https://ncbi.nlm.nih.gov/pubmed/24648448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03455-13
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