Antagonistic Determinants Controlling Replicative and Latent States of Human Cytomegalovirus Infection

The mechanisms by which viruses persist and particularly those by which viruses actively contribute to their own latency have been elusive. Here we report the existence of opposing functions encoded by genes within a polycistronic locus of the human cytomegalovirus (HCMV) genome that regulate cell t...

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Main Authors: Umashankar, Mahadevaiah, Rak, Michael, Bughio, Farah, Zagallo, Patricia, Caviness, Katie, Goodrum, Felicia D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093889/
https://ncbi.nlm.nih.gov/pubmed/24623432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03506-13
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