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Conserved Features of the PB2 627 Domain Impact Influenza Virus Polymerase Function and Replication

Successful replication of influenza virus requires the coordinated expression of viral genes and replication of the genome by the viral polymerase, composed of the subunits PA, PB1, and PB2. Polymerase activity is regulated by both viral and host factors, yet the mechanisms of regulation and how the...

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Hlavní autoři: Kirui, James, Bucci, Michael D., Poole, Daniel S., Mehle, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093881/
https://ncbi.nlm.nih.gov/pubmed/24623411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00508-14
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