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Substitution of Herpes Simplex Virus 1 Entry Glycoproteins with Those of Saimiriine Herpesvirus 1 Reveals a gD-gH/gL Functional Interaction and a Region within the gD Profusion Domain That Is Critical for Fusion

To gain insight into the mechanism of herpesvirus entry into cells, the four glycoproteins that are necessary for herpes simplex virus (HSV) fusion were cloned from the saimiriine herpesvirus 1 (SaHV-1) genome, a primate member of the alphaherpesvirus family. Cell-cell fusion assays indicate that Sa...

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Détails bibliographiques
Auteurs principaux: Fan, Qing, Longnecker, Richard, Connolly, Sarah A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093879/
https://ncbi.nlm.nih.gov/pubmed/24672037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00465-14
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