Reduction of MicroRNA 122 Expression in IFNL3 CT/TT Carriers and during Progression of Fibrosis in Patients with Chronic Hepatitis C

The microRNA miR-122 is highly expressed in the liver and stimulates hepatitis C virus (HCV) replication in vitro. IFNL3 (lambda-3 interferon gene) polymorphisms and the expression of miR-122 have been associated with sustained virological response (SVR) to treatment with pegylated interferon plus r...

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Détails bibliographiques
Auteurs principaux: Estrabaud, Emilie, Lapalus, Martine, Broët, Philippe, Appourchaux, Kevin, Muynck, Simon De, Lada, Olivier, Martinot-Peignoux, Michelle, Bièche, Ivan, Valla, Dominique, Bedossa, Pierre, Marcellin, Patrick, Vidaud, Michel, Asselah, Tarik
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093870/
https://ncbi.nlm.nih.gov/pubmed/24672032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00016-14
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