SCG10 Expression on Activation of Hepatic Stellate Cells Promotes Cell Motility Through Interference with Microtubules

During liver fibrogenesis, quiescent hepatic stellate cells switch their phenotype toward a myofibroblastic-like pattern with a gain in motility. Here, we show that SCG10 (superior cervical ganglia 10) mRNA expression, a microtubule-destabilizing protein that favors cell growth and motility in neuro...

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Detalhes bibliográficos
Main Authors: Paradis, Valerie, Dargere, Delphine, Bieche, Yvan, Asselah, Tarik, Marcellin, Patrick, Vidaud, Michel, Bedossa, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947275/
https://ncbi.nlm.nih.gov/pubmed/20802173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100166
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