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HIV-1 Vpu Antagonism of Tetherin Inhibits Antibody-Dependent Cellular Cytotoxic Responses by Natural Killer Cells

The type I interferon-inducible factor tetherin retains virus particles on the surfaces of cells infected with vpu-deficient human immunodeficiency virus type 1 (HIV-1). While this mechanism inhibits cell-free viral spread, the immunological implications of tethered virus have not been investigated....

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Detalhes bibliográficos
Main Authors: Alvarez, Raymond A., Hamlin, Rebecca E., Monroe, Anthony, Moldt, Brian, Hotta, Mathew T., Rodriguez Caprio, Gabriela, Fierer, Daniel S., Simon, Viviana, Chen, Benjamin K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093850/
https://ncbi.nlm.nih.gov/pubmed/24623433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00449-14
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