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Hyperinsulinemia Promotes Metastasis to the Lung in a Mouse Model of Her2-mediated Breast Cancer

The Her2 oncogene is expressed in approximately 25% of human breast cancers and is associated with metastatic progression and poor outcome. Epidemiological studies report that breast cancer incidence and mortality rates are higher in women with type 2 diabetes. Here we use a mouse model of Her2-medi...

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Bibliographic Details
Main Authors: Ferguson, Rosalyn, Gallagher, Emily, Cohen, Dara, Tobin-Hess, Aviva, Alikhani, Nyosha, Novosyadlyy, Ruslan, Haddad, Nadine, Yakar, Shoshana, LeRoith, Derek
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093836/
https://ncbi.nlm.nih.gov/pubmed/23572162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-12-0333
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