Chemokine treatment rescues profound T-lineage progenitor homing defect after bone marrow transplant conditioning in mice

Development of T cells in the thymus requires continuous importation of T-lineage progenitors from the bone marrow via the circulation. Following bone marrow transplant, recovery of a normal peripheral T-cell pool depends on production of naïve T cells in the thymus; however, delivery of progenitors...

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Библиографические подробности
Главные авторы: Zhang, Shirley L., Wang, Xinxin, Manna, Sugata, Zlotoff, Daniel A., Bryson, Jerrod L., Blazar, Bruce R., Bhandoola, Avinash
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2014
Предметы:
Transplantation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093685/
https://ncbi.nlm.nih.gov/pubmed/24876562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-552794
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