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Intraventricular Topotecan for the Treatment of Neoplastic Meningitis: Five Case Studies

Many systemic cytotoxic agents cannot penetrate the blood-brain barrier. Because of this, in approximately 5% of cancer cases, metastatic disease is seen in the leptomeninges. Without treatment, patients with neoplastic meningitis (NM) generally survive for only a matter of weeks. In the treatment o...

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Bibliografiske detaljer
Main Authors: Walker, Julie, Schultz, Diana, Grisdale, Kathleen, Groves, Morris
Format: Artigo
Sprog:Inglês
Udgivet: Harborside Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093345/
https://ncbi.nlm.nih.gov/pubmed/25031951
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