A Phase 1 Pharmacokinetic Optimal Dosing Study of Intraventricular Topotecan for Children with Neoplastic Meningitis: A Pediatric Brain Tumor Consortium Study

PURPOSE: We performed a phase 1 pharmacokinetic optimal dosing study of intraventricular topotecan (IT), administered daily × 5, to determine whether the maximum tolerated dose of IT topotecan was also the pharmacokinetic optimal dose. PATIENTS AND METHODS: Patients received topotecan administered t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Blaney, Susan M., Tagen, Michael, Onar-Thomas, Arzu, Berg, Stacey L., Gururangan, Sri, Scorsone, Kathleen, Su, Jack, Goldman, Stewart, Kieran, Mark W., Kun, Larry, Boyett, Jim, Stewart, Clinton
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573253/
https://ncbi.nlm.nih.gov/pubmed/23002039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24309
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados