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Role of Ubiquitylation in Controlling Suppressor of Cytokine Signalling 3 (SOCS3) Function and Expression

The realisation that unregulated activation of the Janus kinase–signal transducer and activator of transcription (JAK–STAT) pathway is a key driver of a wide range of diseases has identified its components as targets for therapeutic intervention by small molecule inhibitors and biologicals. In this...

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Hlavní autoři: Williams, Jamie J. L., Munro, Kirsten M. A., Palmer, Timothy M.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092859/
https://ncbi.nlm.nih.gov/pubmed/24886706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells3020546
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