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Mcl-1 Ubiquitination: Unique Regulation of an Essential Survival Protein
Mcl-1 is an anti-apoptotic protein of the Bcl-2 family that is essential for the survival of multiple cell lineages and that is highly amplified in human cancer. Under physiological conditions, Mcl-1 expression is tightly regulated at multiple levels, involving transcriptional, post-transcriptional...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4092850/ https://ncbi.nlm.nih.gov/pubmed/24814761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells3020418 |
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