Sphingosine Kinase-2 Maintains Viral Latency and Survival for KSHV-Infected Endothelial Cells

Phosphorylation of sphingosine by sphingosine kinases (SphK1 and SphK2) generates sphingosine-1-phosphate (S1P), a bioactive sphingolipid which promotes cancer cell survival and tumor progression in vivo. We have recently reported that targeting SphK2 induces apoptosis for human primary effusion lym...

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Главные авторы: Dai, Lu, Plaisance-Bonstaff, Karlie, Voelkel-Johnson, Christina, Smith, Charles D., Ogretmen, Besim, Qin, Zhiqiang, Parsons, Chris
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092155/
https://ncbi.nlm.nih.gov/pubmed/25010828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102314
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