Sphingosine Kinase-2 Maintains Viral Latency and Survival for KSHV-Infected Endothelial Cells

Phosphorylation of sphingosine by sphingosine kinases (SphK1 and SphK2) generates sphingosine-1-phosphate (S1P), a bioactive sphingolipid which promotes cancer cell survival and tumor progression in vivo. We have recently reported that targeting SphK2 induces apoptosis for human primary effusion lym...

Full description

Saved in:
Bibliographic Details
Main Authors: Dai, Lu, Plaisance-Bonstaff, Karlie, Voelkel-Johnson, Christina, Smith, Charles D., Ogretmen, Besim, Qin, Zhiqiang, Parsons, Chris
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092155/
https://ncbi.nlm.nih.gov/pubmed/25010828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102314
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items