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Sphingosine Kinase-2 Maintains Viral Latency and Survival for KSHV-Infected Endothelial Cells
Phosphorylation of sphingosine by sphingosine kinases (SphK1 and SphK2) generates sphingosine-1-phosphate (S1P), a bioactive sphingolipid which promotes cancer cell survival and tumor progression in vivo. We have recently reported that targeting SphK2 induces apoptosis for human primary effusion lym...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4092155/ https://ncbi.nlm.nih.gov/pubmed/25010828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102314 |
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