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Pancreatic Insulin-Producing Cells Differentiated from Human Embryonic Stem Cells Correct Hyperglycemia in SCID/NOD Mice, an Animal Model of Diabetes

BACKGROUND: Human pancreatic islet transplantation is a prospective curative treatment for diabetes. However, the lack of donor pancreases greatly limits this approach. One approach to overcome the limited supply of donor pancreases is to generate functional islets from human embryonic stem cells (h...

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Main Authors: Hua, Xiu-feng, Wang, Yan-wei, Tang, Yu-xiao, Yu, Sheng-qiang, Jin, Shao-hua, Meng, Xiao-mei, Li, Hua-feng, Liu, Fu-jun, Sun, Qiang, Wang, Hai-yan, Li, Jian-yuan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092102/
https://ncbi.nlm.nih.gov/pubmed/25009980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102198
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