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PDX1-engineered embryonic stem cell-derived insulin producing cells regulate hyperglycemia in diabetic mice

BACKGROUND: Type 1 diabetes can be treated by the transplantation of cadaveric whole pancreata or isolated pancreatic islets. However, this form of treatment is hampered by the chronic shortage of cadaveric donors. Embryonic stem (ES) cell-derived insulin producing cells (IPCs) offer a potentially n...

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Detalhes bibliográficos
Main Authors: Raikwar, Sudhanshu P, Zavazava, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560994/
https://ncbi.nlm.nih.gov/pubmed/23369186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-1440-1-19
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