Activity of 129 Single-Agent Drugs in 228 Phase I and II Clinical Trials in Multiple Myeloma

BACKGROUND: More than 400 preclinical studies report ≥ 1 compound as cytotoxic to multiple myeloma (MM) cells; however, few of these agents became relevant in the clinic. Thus, the utility of such assays in predicting future clinical value is debatable. PATIENTS AND METHODS: We examined the applicat...

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Bibliographic Details
Main Authors: Kortuem, K. Martin, Zidich, Kaitlyn, Schuster, Steven R., Khan, Meaghan L., Jimenez-Zepeda, Victor H., Mikhael, Joseph R., Fonseca, Rafael, Stewart, A. Keith
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092053/
https://ncbi.nlm.nih.gov/pubmed/24565465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clml.2013.12.015
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