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Basal forebrain atrophy and cortical amyloid deposition in nondemented elderly subjects

BACKGROUND: Both neurodegeneration of the cholinergic basal forebrain (BF) and deposition of beta-amyloid are early events in the course of Alzheimer's disease (AD). Associations between increased amyloid pathology and cholinergic atrophy have been described in autopsy studies. METHODS: We used...

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Autori principali: Grothe, Michel J., Ewers, Michael, Krause, Bernd, Heinsen, Helmut, Teipel, Stefan J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092050/
https://ncbi.nlm.nih.gov/pubmed/24418052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2013.09.011
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