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Atrophy of the cholinergic basal forebrain over the adult age range and in early stages of Alzheimer´s disease

BACKGROUND: The basal forebrain cholinergic system (BFCS) is known to undergo moderate neurodegenerative changes during normal aging as well as severe atrophy in Alzheimer´s disease (AD). However, there is a controversy on how the cholinergic lesion in AD relates to early and incipient stages of the...

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Detalles Bibliográficos
Autores principales: Grothe, Michel, Heinsen, Helmut, Teipel, Stefan J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701122/
https://ncbi.nlm.nih.gov/pubmed/21816388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.06.019
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