CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis

OBJECTIVE: Chemokines are known to play an important role in the pathophysiology of alcoholic hepatitis (AH), a form of acute-on-chronic liver injury frequently mediated by gut derived lipopolysaccharide (LPS). In our study, we hypothesise that chemokine CCL20, one of the most upregulated chemokines...

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Autors principals: Affò, Silvia, Morales-Ibanez, Oriol, Rodrigo-Torres, Daniel, Altamirano, José, Blaya, Delia, Dapito, Dianne H, Millán, Cristina, Coll, Mar, Caviglia, Jorge M, Arroyo, Vicente, Caballería, Juan, Schwabe, Robert F, Ginès, Pere, Bataller, Ramón, Sancho-Bru, Pau
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092046/
https://ncbi.nlm.nih.gov/pubmed/24415562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-306098
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