Combined effects of asbestos and cigarette smoke on the development of lung adenocarcinoma: Different carcinogens may cause different genomic changes

The carcinogens in cigarette smoke are distinct from asbestos. However, an understanding of their differential effects on lung adenocarcinoma development remains elusive. We investigated loss of heterozygosity (LOH) and the p53 mutation in 132 lung adenocarcinomas, for which asbestos body burden (AB...

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Main Authors: INAMURA, KENTARO, NINOMIYA, HIRONORI, NOMURA, KIMIE, TSUCHIYA, EIJU, SATOH, YUKITOSHI, OKUMURA, SAKAE, NAKAGAWA, KEN, TAKATA, AYAKO, KOHYAMA, NORIHIKO, ISHIKAWA, YUICHI
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091886/
https://ncbi.nlm.nih.gov/pubmed/24926563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2014.3263
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