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Functional analysis of human microsomal epoxide hydrolase genetic variants

Human microsomal epoxide hydrolase (EPHX1) is active in the metabolism of many potentially carcinogenic or otherwise genotoxic epoxides, such as those derived from the oxidation of polyaromatic hydrocarbons. EPHX1 is polymorphic and encodes allelic variation at least two amino acid positions, Y113H...

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Bibliografiske detaljer
Main Authors: Hosagrahara, Vinayak P., Rettie, Allan E., Hassett, Christopher, Omiecinski, Curtis J.
Format: Artigo
Sprog:Inglês
Udgivet: 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091877/
https://ncbi.nlm.nih.gov/pubmed/15535985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2004.07.004
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