A comprehensive protein–protein interactome for yeast PAS kinase 1 reveals direct inhibition of respiration through the phosphorylation of Cbf1

Per-Arnt-Sim (PAS) kinase is a sensory protein kinase required for glucose homeostasis in yeast, mice, and humans, yet little is known about the molecular mechanisms of its function. Using both yeast two-hybrid and copurification approaches, we identified the protein–protein interactome for yeast PA...

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Autors principals: DeMille, Desiree, Bikman, Benjamin T., Mathis, Andrew D., Prince, John T., Mackay, Jordan T., Sowa, Steven W., Hall, Tacie D., Grose, Julianne H.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091833/
https://ncbi.nlm.nih.gov/pubmed/24850888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-10-0631
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