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Chronic AT2 receptor activation attenuates renal AT1 receptor function and blood pressure in obese Zucker rats
Abnormal regulation of the renin angiotensin system such as enhanced renal AT1R function and reduced ACE2 activity contributes to obesity-related hypertension. Here we tested whether long-term AT2R activation affects renal function in obesity using lean and obese Zucker rats treated with the AT2R ag...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091804/ https://ncbi.nlm.nih.gov/pubmed/23823602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.193 |
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