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High Na intake increases renal angiotensin II levels and reduces expression of the ACE2-AT(2)R-MasR axis in obese Zucker rats

High sodium intake is known to regulate the renal renin-angiotensin system (RAS) and is a risk factor for the pathogenesis of obesity-related hypertension. The complex nature of the RAS reveals that its various components may have opposing effects on natriuresis and blood pressure regulation. We hyp...

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Detalhes bibliográficos
Main Authors: Samuel, Preethi, Ali, Quaisar, Sabuhi, Rifat, Wu, Yonnie, Hussain, Tahir
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433866/
https://ncbi.nlm.nih.gov/pubmed/22592638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00097.2012
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