Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin

Variation in plasma levels of cortisol, an essential hormone in the stress response, is associated in population-based studies with cardio-metabolic, inflammatory and neuro-cognitive traits and diseases. Heritability of plasma cortisol is estimated at 30–60% but no common genetic contribution has be...

সম্পূর্ণ বিবরণ

সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Bolton, Jennifer L., Hayward, Caroline, Direk, Nese, Lewis, John G., Hammond, Geoffrey L., Hill, Lesley A., Anderson, Anna, Huffman, Jennifer, Wilson, James F., Campbell, Harry, Rudan, Igor, Wright, Alan, Hastie, Nicholas, Wild, Sarah H., Velders, Fleur P., Hofman, Albert, Uitterlinden, Andre G., Lahti, Jari, Räikkönen, Katri, Kajantie, Eero, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G., Kaakinen, Marika, Järvelin, Marjo-Riitta, Timpson, Nicholas J., Davey Smith, George, Ring, Susan M., Evans, David M., St Pourcain, Beate, Tanaka, Toshiko, Milaneschi, Yuri, Bandinelli, Stefania, Ferrucci, Luigi, van der Harst, Pim, Rosmalen, Judith G. M., Bakker, Stephen J. L., Verweij, Niek, Dullaart, Robin P. F., Mahajan, Anubha, Lindgren, Cecilia M., Morris, Andrew, Lind, Lars, Ingelsson, Erik, Anderson, Laura N., Pennell, Craig E., Lye, Stephen J., Matthews, Stephen G., Eriksson, Joel, Mellstrom, Dan, Ohlsson, Claes, Price, Jackie F., Strachan, Mark W. J., Reynolds, Rebecca M., Tiemeier, Henning, Walker, Brian R.
বিন্যাস: Artigo
ভাষা:Inglês
প্রকাশিত: Public Library of Science 2014
বিষয়গুলি:
Research Article
অনলাইন ব্যবহার করুন:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091794/
https://ncbi.nlm.nih.gov/pubmed/25010111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004474
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