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Regulatory crosstalk and interference between the xenobiotic and hypoxia sensing pathways at the AhR-ARNT-HIF1α signaling node

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates many of the responses to toxic environmental chemicals such as TCDD or dioxin-like PCBs. To regulate gene expression, the AhR requires its binding partner, the aryl hydrocarbon receptor nuclear translocator...

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Bibliographic Details
Main Authors: Vorrink, Sabine U., Domann, Frederick E.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091760/
https://ncbi.nlm.nih.gov/pubmed/24824450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2014.05.001
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