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Transmission of mitochondrial mutations and action of purifying selection in Drosophila

It is not known how selection affects mutations on the multicopied mitochondrial genome (1–11). We transferred cytoplasm between D. melanogaster embryos carrying mitochondrial mutations to create heteroplasmic lines transmitting two mitochondrial genotypes. Increased temperature imposed selection ag...

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Detalles Bibliográficos
Main Authors: Ma, Hansong, Xu, Hong, O’Farrell, Patrick H.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091738/
https://ncbi.nlm.nih.gov/pubmed/24614071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2919
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