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Thrombospondin-2 facilitates assembly of a type I collagen-rich matrix in marrow stromal cells undergoing osteoblastic differentiation
We examined the effects of TSP2 deficiency on assembly of collagenous extracellular matrix (ECM) by primary marrow-derived mesenchymal stromal cells (MSC) undergoing osteoblast differentiation in culture. After 30 days, wild-type cells had accumulated and mineralized a collagen-rich insoluble matrix...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091640/ https://ncbi.nlm.nih.gov/pubmed/23763373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03008207.2013.811236 |
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