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Thrombospondin-2 facilitates assembly of a type I collagen-rich matrix in marrow stromal cells undergoing osteoblastic differentiation

We examined the effects of TSP2 deficiency on assembly of collagenous extracellular matrix (ECM) by primary marrow-derived mesenchymal stromal cells (MSC) undergoing osteoblast differentiation in culture. After 30 days, wild-type cells had accumulated and mineralized a collagen-rich insoluble matrix...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Alford, Andrea I., Golicz, Andrew Z., Cathey, Amber Lee, Reddy, Anita B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091640/
https://ncbi.nlm.nih.gov/pubmed/23763373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03008207.2013.811236
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