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A clinically useful approach to enhance immunological memory and antitumor immunity
Persistence of vaccine-induced immune responses, not the initial magnitude, best correlates with protective antitumor immunity. In mice, oligonucleotide aptamer-targeted siRNA inhibition of mammalian target of rapamycin (mTOR) activity in activated CD8+ T cells promotes their differentiation into fu...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091317/ https://ncbi.nlm.nih.gov/pubmed/25057446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.28811 |
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