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Deficient autophagy unravels the ROS paradox in chronic granulomatous disease
Autophagy defects resulting in inflammation appear to be a key feature in the pathogenesis of Crohn colitis. An inflammatory colitis indistinguishable from Crohn disease is described in patients with chronic granulomatous disease (CGD). Patients with CGD have a mutated NADPH complex and are therefor...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091174/ https://ncbi.nlm.nih.gov/pubmed/24879159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.28638 |
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