Disruption of chaperone-mediated autophagy-dependent degradation of MEF2A by oxidative stress-induced lysosome destabilization

Oxidative stress has been implicated in both normal aging and various neurodegenerative disorders and it may be a major cause of neuronal death. Chaperone-mediated autophagy (CMA) targets selective cytoplasmic proteins for degradation by lysosomes and protects neurons against various extracellular s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhang, Li, Sun, Yang, Fei, Mingjian, Tan, Cheng, Wu, Jing, Zheng, Jie, Tang, Jiqing, Sun, Wei, Lv, Zhaoliang, Bao, Jiandong, Xu, Qiang, Yu, Huixin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2014
Gaiak:
Basic Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091166/
https://ncbi.nlm.nih.gov/pubmed/24879151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.28477
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