Essential control of mitochondrial morphology and function by chaperone-mediated autophagy through degradation of PARK7

As a selective degradation system, chaperone-mediated autophagy (CMA) is essential for maintaining cellular homeostasis and survival under stress conditions. Increasing evidence points to an important role for the dysfunction of CMA in the pathogenesis of Parkinson disease (PD). However, the mechani...

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Vydáno v:Autophagy
Hlavní autoři: Wang, Bao, Cai, Zhibiao, Tao, Kai, Zeng, Weijun, Lu, Fangfang, Yang, Ruixin, Feng, Dayun, Gao, Guodong, Yang, Qian
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Basic Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968227/
https://ncbi.nlm.nih.gov/pubmed/27171370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1179401
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