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Establishment of a system for monitoring endoplasmic reticulum redox state in mammalian cells

The endoplasmic reticulum (ER) performs a critical role in the oxidative folding of nascent proteins such that perturbations to ER homeostasis may lead to protein misfolding and subsequent pathological processes. Among the mechanisms for maintaining ER homeostasis is a redox regulation, which is a c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kanekura, Kohsuke, Ishigaki, Shinsuke, Merksamer, Philip I., Papa, Feroz R., Urano, Fumihiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090936/
https://ncbi.nlm.nih.gov/pubmed/24042438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2013.112
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