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Genetic ablation of β-catenin inhibits the proliferative phenotype of mouse liver adenomas

BACKGROUND: Aberrant activation of Wnt/β-catenin has been implicated in various cancer-related processes, for example, proliferation or tumour cell survival. However, the exact mechanism by which β-catenin provides liver tumour cells with a selective advantage is still unclear. This study was aimed...

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Библиографические подробности
Главные авторы: Singh, Y, Port, J, Schwarz, M, Braeuning, A
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090738/
https://ncbi.nlm.nih.gov/pubmed/24874479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.275
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