Assessing the function of homologous recombination DNA repair in malignant pleural effusion (MPE) samples

BACKGROUND: Patients with malignant pleural effusions (MPEs) generally have advanced disease with poor survival and few therapeutic options. Cells within MPEs may be used to stratify patients for targeted therapy. Targeted therapy with poly(ADP ribose) polymerase inhibitors (PARPi) depends on identi...

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Hlavní autoři: Patterson, M J, Sutton, R E, Forrest, I, Sharrock, R, Lane, M, Kaufmann, A, O'Donnell, R, Edmondson, R J, Wilson, B T, Curtin, N J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
Translational Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090730/
https://ncbi.nlm.nih.gov/pubmed/24867690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.261
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