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The role of TMPRSS2:ERG in molecular stratification of PCa and its association with tumor aggressiveness: a study in Brazilian patients

Recurrent gene fusions between the genes TMPRSS2 and ERG have been described in prostate cancer (PCa) and are found in 27% to 79% of radical prostatectomy. This fusion transcription results in ERG overexpression, which can be detected by immunohistochemistry (IHC) and provide a potential diagnostic...

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Detalhes bibliográficos
Main Authors: Eguchi, Flávia C., Faria, Eliney F., Neto, Cristovam Scapulatempo, Longatto-Filho, Adhemar, Zanardo-Oliveira, Cleyton, Taboga, Sebastião R., Campos, Silvana G. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090618/
https://ncbi.nlm.nih.gov/pubmed/25007891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05640
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