Association Between Combined TMPRSS2:ERG and PCA3 RNA Urinary Testing and Detection of Aggressive Prostate Cancer

IMPORTANCE: Potential survival benefits from treating aggressive (Gleason score, ≥7) early-stage prostate cancer are undermined by harms from unnecessary prostate biopsy and overdiagnosis of indolent disease. OBJECTIVE: To evaluate the a priori primary hypothesis that combined measurement of PCA3 an...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Sanda, Martin G., Feng, Ziding, Howard, David H., Tomlins, Scott A., Sokoll, Lori J., Chan, Daniel W., Regan, Meredith M., Groskopf, Jack, Chipman, Jonathan, Patil, Dattatraya H., Salami, Simpa S., Scherr, Douglas S., Kagan, Jacob, Srivastava, Sudhir, Thompson, Ian M., Siddiqui, Javed, Fan, Jing, Joon, Aron Y., Bantis, Leonidas E., Rubin, Mark A., Chinnayian, Arul M., Wei, John T., Bidair, Mohamed, Kibel, Adam, Lin, Daniel W., Lotan, Yair, Partin, Alan, Taneja, Samir
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710334/
https://ncbi.nlm.nih.gov/pubmed/28520829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2017.0177
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