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Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia

The Fosb gene encodes subunits of the activator protein-1 transcription factor complex. Two mature mRNAs, Fosb and ΔFosb, encoding full-length FOSB and ΔFOSB proteins respectively, are formed by alternative splicing of Fosb mRNA. Fosb products are expressed in several brain regions. Moreover, Fosb-n...

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Bibliografiska uppgifter
Huvudupphovsmän: Nomaru, Hiroko, Sakumi, Kunihiko, Katogi, Atsuhisa, Ohnishi, Yoshinori N, Kajitani, Kosuke, Tsuchimoto, Daisuke, Nestler, Eric J., Nakabeppu, Yusaku
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090226/
https://ncbi.nlm.nih.gov/pubmed/24771617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22680
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