Transdifferentiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha.

Skeletal muscle and adipose tissue development often has a reciprocal relationship in vivo, particularly in myodystrophic states. We have investigated whether determined myoblasts with no inherent adipogenic potential can be induced to transdifferentiate into mature adipocytes by the ectopic express...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Hu, E, Tontonoz, P, Spiegelman, B M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40901/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568232/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.21.9856
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