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Transdifferentiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha.

Skeletal muscle and adipose tissue development often has a reciprocal relationship in vivo, particularly in myodystrophic states. We have investigated whether determined myoblasts with no inherent adipogenic potential can be induced to transdifferentiate into mature adipocytes by the ectopic express...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Hu, E, Tontonoz, P, Spiegelman, B M
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1995
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40901/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568232/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.21.9856
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