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Tumor targeting RGD conjugated bio-reducible polymer for VEGF siRNA expressing plasmid delivery

Targeted delivery of therapeutic genes to the tumor site is critical for successful and safe cancer gene therapy. The arginine grafted bio-reducible poly (cystamine bisacrylamide-diaminohexane, CBA-DAH) polymer (ABP) conjugated poly (amido amine) (PAMAM), PAM-ABP (PA) was designed previously as an e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Hyun Ah, Nam, Kihoon, Kim, Sung Wan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090046/
https://ncbi.nlm.nih.gov/pubmed/24894645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.05.021
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