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A chromatin-based mechanism for limiting divergent non-coding transcription

In addition to their annotated transcript, many eukaryotic mRNA promoters produce divergent noncoding transcripts. To define determinants of divergent promoter directionality we used genomic replacement experiments. Sequences within non-coding transcripts specified their degradation pathways, and fu...

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書誌詳細
主要な著者: Marquardt, Sebastian, Escalante-Chong, Renan, Pho, Nam, Wang, Jue, Churchman, Stirling, Springer, Michael, Buratowski, Stephen
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090027/
https://ncbi.nlm.nih.gov/pubmed/24949978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.04.036
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