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A chromatin-based mechanism for limiting divergent non-coding transcription

In addition to their annotated transcript, many eukaryotic mRNA promoters produce divergent noncoding transcripts. To define determinants of divergent promoter directionality we used genomic replacement experiments. Sequences within non-coding transcripts specified their degradation pathways, and fu...

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Detalhes bibliográficos
Main Authors: Marquardt, Sebastian, Escalante-Chong, Renan, Pho, Nam, Wang, Jue, Churchman, Stirling, Springer, Michael, Buratowski, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090027/
https://ncbi.nlm.nih.gov/pubmed/24949978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.04.036
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