Induction of MicroRNA-21 with Exogenous Hydrogen Sulfide Attenuates Myocardial Ischemic and Inflammatory Injury in Mice

BACKGROUND: Maintaining physiological levels of hydrogen sulfide (H(2)S) during ischemia is necessary to limit injury to the heart. Due to the anti-inflammatory effects of H(2)S, we proposed that the H(2)S donor, Na(2)S, would attenuate myocardial injury through upregulation of ‘protective’ microRNA...

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Detalhes bibliográficos
Main Authors: Toldo, Stefano, Das, Anindita, Mezzaroma, Eleonora, Chau, Vinh Q., Marchetti, Carlo, Durrant, David, Samidurai, Arun, Van Tassell, Benjamin W., Yin, Chang, Ockaili, Ramzi A., Vigneshwar, Navin, Mukhopadhyay, Nitai D., Kukreja, Rakesh C., Abbate, Antonio, Salloum, Fadi N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090021/
https://ncbi.nlm.nih.gov/pubmed/24825878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.113.000381
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