Induction of MicroRNA-21 with Exogenous Hydrogen Sulfide Attenuates Myocardial Ischemic and Inflammatory Injury in Mice

BACKGROUND: Maintaining physiological levels of hydrogen sulfide (H(2)S) during ischemia is necessary to limit injury to the heart. Due to the anti-inflammatory effects of H(2)S, we proposed that the H(2)S donor, Na(2)S, would attenuate myocardial injury through upregulation of ‘protective’ microRNA...

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Hlavní autoři: Toldo, Stefano, Das, Anindita, Mezzaroma, Eleonora, Chau, Vinh Q., Marchetti, Carlo, Durrant, David, Samidurai, Arun, Van Tassell, Benjamin W., Yin, Chang, Ockaili, Ramzi A., Vigneshwar, Navin, Mukhopadhyay, Nitai D., Kukreja, Rakesh C., Abbate, Antonio, Salloum, Fadi N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090021/
https://ncbi.nlm.nih.gov/pubmed/24825878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.113.000381
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