Combined Mössbauer, multi-edge X-ray absorption spectroscopic, and density functional theoretical study of the radical SAM enzyme spore photoproduct lyase

Spore photoproduct lyase (SPL), a member of the radical SAM superfamily, catalyzes the direct reversal of the spore photoproduct (SP), a thymine dimer specific to bacterial spores, to two thymines. SPL requires S-adenosyl-L-methionine (SAM) and a redox active [4Fe-4S] cluster for catalysis. Mössbaue...

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Autori principali: Silver, Sunshine C., Gardenghi, David J., Naik, Sunil G., Shepard, Eric M., Huynh, Boi Hanh, Szilagyi, Robert K., Broderick, Joan B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089880/
https://ncbi.nlm.nih.gov/pubmed/24532333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-014-1104-y
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